Five days stay and by train, Venice to Naples;
Two days car Naples, Pompeii, Herculaneum, Amalfi Coast;
Four days Naples ferry to Sicily: Palermo; Monreale, Erice, Trapani, Marsala, Selinunte, Agrigento, Gela, Casale (Villa Romana), Enna, Mount Etna, Randazzo, Capo D'Orlando, Cefalu, Termini, Solunte and Palermo.
Three days Ferry to Naples again, Anzio, Ostia Antica, and Rome.
See also www.europeroadways.com.